Aberrant DNA methylation involved in obese women with systemic insulin resistance

Zhang Shao-Jun; Wang Yan; Yang Yan-Lan; Zheng Hong

doi:10.1515/biol-2018-0024

Open Life Sciences (Jun 2018)

Aberrant DNA methylation involved in obese women with systemic insulin resistance

Zhang Shao-Jun,
Wang Yan,
Yang Yan-Lan,
Zheng Hong

Affiliations

Zhang Shao-Jun: Department of Endocrinology, The People’s Hospital of Shanxi Province, Taiyuan, Shanxi 030012, China
Wang Yan: Medical Laboratory Diagnosis Center, Jinan Central Hospital, Jinan, Shandong 250013, China
Yang Yan-Lan: Department of Endocrinology, The People’s Hospital of Shanxi Province, Taiyuan, Shanxi 030012, China
Zheng Hong: Department of Endocrinology, The Second Affiliated Hospital of Dalian Medical University, No. 467 Zhongshan Road, Shahekou District, Dalian, Liaoning 116023, China

DOI: https://doi.org/10.1515/biol-2018-0024
Journal volume & issue: Vol. 13, no. 1
pp. 201 – 207

Abstract

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Epigenetics has been recognized as a significant regulator in many diseases. White adipose tissue (WAT) epigenetic dysregulation is associated with systemic insulin resistance (IR). The aim of this study was to survey the differential methylation of genes in obese women with systemic insulin resistance by DNA methylation microarray.

Published in Open Life Sciences

ISSN: 2391-5412 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Biology (General)
Website: http://www.degruyter.com/view/j/biol

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