Nature Communications (Jan 2023)

Uncovering the mechanism for aggregation in repeat expanded RNA reveals a reentrant transition

  • Ofer Kimchi,
  • Ella M. King,
  • Michael P. Brenner

DOI
https://doi.org/10.1038/s41467-023-35803-x
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 9

Abstract

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RNA molecules aggregate in certain conditions, but how and why remains unclear. Here the authors develop a model that quantitatively explains the conditions and mechanism of RNA aggregation, and predicts a surprising non-monotonicity in the transition.