Biomedical and Biotechnology Research Journal (Jan 2018)
Erythema nodosum with oral and genital ulcers: A case of behçet's disease
Abstract
Behçet's disease (BD) is a chronic, relapsing, multisystemic disorder characterized by mucocutaneous, ocular, vascular, and central nervous system manifestations. The clinical spectrum includes oral and genital ulcerations, uveitis, and vascular, neurological, articular, renal, and gastrointestinal manifestations. The etiopathogenesis of the disease remains unknown although genetic predisposition, environmental factors, and immunological abnormalities have been implicated. It usually affects young adults. The case of a 22-year-old female who presented with fever, recurrent oral ulcers, genital ulcers, arthralgia, and erythema nodosum is presented here. A diagnosis of BD based on clinical criteria was made. The patient was treated with colchicine 1 mg/day which had beneficial effects on the reduction in size and recurrence of mucocutaneous ulcers.
Keywords