Sub-panretinal photocoagulation <i>vs</i> panretinal photocoagulation for pre-proliferative diabetic retinopathy: a prospective non-randomized study

Abstract

AIM: To evaluate the efficacy and safety of panretinal photocoagulation(PRP)and sub-panretinal photocoagulation(sub-PRP)for pre-proliferative diabetic retinopathy(PPDR)and its effect for macular. METHODS: From January to December 2014, 61 patients with PPDR were divided into observation group(24 patients with 43 eyes who received sub-PRP)and control group(37 patients with 66 eyes who received PRP). Their clinical data and follow-up results were reviewed. RESULTS: The efficiency rate of visual acuity and of retinopathy were 77% and 81% in observation group at 6mo after treatments. The two indicators in control group were 76% and 80% and the difference on the two indicators between the two groups were not statistically significant(P>0.05).The central macular thickness and volume of macula reached peak in both group at 1mo after photocoagulation and compared to those before treatments, the differences were statistically significant(PPP>0.05), while those of panretinal photocoagulation group were higher than those before treatments and those of observation group(PPCONCLUSION: The effect of sub-PRP on PPDR is comparable to that of PRP, while the effect on the macula is smaller.

Keywords

• proliferative diabetic retinopathy
• sub-panretinal photocoagulation
• panretinal photocoagulation
• optical coherence tomography