Foods (Jan 2022)

Egg Yolk Protein Water Extracts Modulate the Immune Response in BALB/c Mice with Immune Dysfunction Caused by Forced Swimming

  • Mijoo Choi,
  • Jae-Hoon Lee,
  • Yun-Jung Lee,
  • Hyun-Dong Paik,
  • Eunju Park

DOI
https://doi.org/10.3390/foods11010121
Journal volume & issue
Vol. 11, no. 1
p. 121

Abstract

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The objective of this study was to determine the immunomodulatory effects of egg yolk protein–water extract (EYW) on splenocyte proliferation, cytokine secretion, immunoglobulin production, and NK cell cytotoxic activity in BALB/c mice. The forced swimming test (FST) was used to provide a model for suppressing immune regulation. The proliferation of B cells in the EYW supplementation group was significantly increased from the level to which it was reduced by the FST (from 40.9% to 81.8%, p p p p < 0.05). These data suggest that EYW has potential as an immunomodulatory agent in the food and/or pharmaceutical industries.

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