ACQUIRED HEMOLYTIC ANEMIA

Journal of Evidence Based Medicine and Healthcare. 2015;2(18):2699-2706 DOI 10.18410/jebmh/395

 

Journal Homepage

Journal Title: Journal of Evidence Based Medicine and Healthcare

ISSN: 2349-2562 (Print); 2349-2570 (Online)

Publisher: Level Up Business Center

Society/Institution: Level Up Business Center

LCC Subject Category: Medicine: Medicine (General): General works

Country of publisher: India

Language of fulltext: English

Full-text formats available: PDF

 

AUTHORS

Veda (P .)
Srinivasamurthy (V .)
Pushpalatha ( K)

EDITORIAL INFORMATION

Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 8 weeks

 

Abstract | Full Text

Acquired hemolytic anemia is a group of disorders in which premature destruction of red cells is triggered by extrinsic factors. In this study, we have evaluated 38 cases of acquired hemolytic anemia. Immune hemolysis accounted for 52 . 6% (n=20) and fragmentation hemolysis 44 . 7% (n=17) of acquired hemolytic anemia. Autoimmune hemolytic anemia (AIHA) and microangiopathic hemolytic anemia (MHA) surfaced as the two most frequent causes accounting for 44 . 7% (n=17) and 39 . 5% (n=15) of acquired hemolysis. E rythrocyte morphology gives valuable clues concerning the cause of hemolysis. Spherocytes were observed in 94% (n=16) cases of immune hemolytic anemia. Schistocytes were observed in all cases of microangiopathic hemolytic anemia (MHA). In addition to schis tocytes, microspherocytes were seen in 40% of MHA. Precise identification of spherocytes, schistocytes and microspherocytes is very important as it gives valuable information regarding the cause of acquired hemolysis.