Ветеринария сегодня (Sep 2020)

Bile microbiocenosis in cats suffering from acute cholangiohepatitis

  • A. A. Rudenko,
  • D. S. Usenko,
  • A. F. Rudenko

DOI
https://doi.org/10.29326/2304-196X-2020-3-34-193-198
Journal volume & issue
Vol. 0, no. 3
pp. 193 – 198

Abstract

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Commensal microorganisms are responsible for numerous diseases of animals, including diseases of internal organs (gastroenteritis, pneumonia, nephritis, hepatitis, cholecystitis, etc.). Cholangiohepatitis, one of the most common liver diseases in cats, is often fatal. The focus of the study was the bile of cats, suffering from acute cholangiohepatitis. The bile was sampled using non-lethal method guided by USG. The bile amount, taken from cats by percutaneous puncture of the gall bladder, was 2.6 ± 0.85 cm3. No complications following the cholecystocentesis were observed in the animals. The microbiocenosis of bile from 51 cats was studied. Acute fe line neutrophilic cholangiohepatitis is mostly caused by commensal bacteria. The range of bacterial pathogens includes the isolates of Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, Enterobacter aerogenes, Staphylococcus epidermidis, Proteus vulgaris, Proteus mirabilis, Enterobacter cloacae, Citrobacter freundii. The infectious process was caused by two-component associations in 75% of cases, and by three-component associations in 25%. Most common polycomponent bacterial associations included E. faecalis + E. coli (26.9%), less common – E. aerogenes + E. coli (15.4%), P. vulgaris + E. coli (11.5%), S. aureus + E. coli (11.5%), rarely – P. aeruginosa + E. coli (7.7%), S. aureus + E. cloacae (3.9%), S. aureus + E. faecalis (3.9%), P. mirabilis + E. coli (3.9%), S. epidermidis + E. coli (3.9%), E. coli + S. epidermidis + E. faecalis (3.9%), P. aeruginosa + E. coli + S. epidermidis (3.9%), E. faecalis + E. coli + C. freundii (3.9%). The predominant component of the mentioned associations is E. coli serovars O101 (28.9%), O41 (2.0%), O141 (15.6%), O26 (13.3%), O138 (13.3%), O15 (6.7%) and O33 (2.2%). It was established that 76.25% of commensal microorganism isolates, recovered from the bile of cats, suffering from feline cholangiohepatitis, were pathogenic for white mice.

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