Romanian Neurosurgery (Dec 2013)

Use of heparin in neurointervention

  • M. Zenteno,
  • L. R. Moscote-Salazar,
  • H. Alvis-Miranda,
  • A. Lee

Journal volume & issue
Vol. 20, no. 4

Abstract

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Background: The use of heparin is routine in endovascular procedures as a strategy in many centers that perform neurointerventional procedures to prevent occlusion of the catheters, but the use of this drug carries risks such as heparin-induced thrombocytopenia. Objective: The purpose of this paper is to present a review of the literature. Material and methods: We conducted an extensive search and review of published papers about heparin and neurointerventional procedures. Results: The evidence in the literature is weak in relation to the use of heparin and the reduction of embolic effects associated with their use in endovascular procedures. Conclusion: The evidence on the use of heparin for the prevention of thromboembolic events in endovascular procedures are of low quality. There is insufficient evidence to conclude a potential benefit of heparin is useful in neurointerventional procedures. Prospective studies are needed to determine the effectiveness of heparin and avoid exposing patients to potential risks.

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