Nature Communications (Jul 2021)
Xanthomonas effector XopR hijacks host actin cytoskeleton via complex coacervation
Abstract
Bacterial pathogens can subvert host cell processes through secreted proteins but the precise mechanisms and repertoire of proteins remains unclear. Here the authors report that a bacterial effector protein of Xanthomonas campestris, XopR, undergoes liquid-liquid phase separation to hijack the host cell actin cytoskeleton.