Oxidative and adhesive responses of human neutrophils to nitrovasodilators in vitro: the role of protein kinases

Abstract

Background: Sodium nitroprusside (SNP) and molsidomine are used in the treatment of coronary heart disease. Since the neutrophils play a pathological role in ischaemic heart disease, it is important to understand the direct action of nitrovasodilators on their function.

Keywords

• Nitrovasodilators
• Neutrophils
• Respiratory burst
• Protein kinases
• Adherence.