Revista de la Facultad de Medicina Humana (Jan 2023)

Identification of Human Papillomavirus genotypes in juvenile laryngeal papillomatosis. Three-year experience in a concentration hospital in Puebla, Mexico

  • Arturo García-Galicia,
  • Clotilde Margarita Andrade-Bonilla,
  • Verónica Vallejo-Ruiz,
  • Blanca Elena Vallejo-Domínguez,
  • Janeth Ramírez-Mendoza,
  • Álvaro José Montiel-Jarquín,
  • Nancy Rosalía Bertado-Ramírez,
  • Jorge Loría-Castellanos

DOI
https://doi.org/10.25176/RFMH.v23i1.5088
Journal volume & issue
Vol. 23, no. 1
pp. 87 – 92

Abstract

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uvenile laryngeal papillomatosis (JLP) is a chronic benign disease of viral etiology, with an aggressive clinical course. In Mexico, the genotypes of the Human Papilloma Virus (HPV) that cause the disease have been poorly studied. The aim of this study was to identify HPV genotypes in PLJ patients. A descriptive and retrospective study was carried out, the records of patients with PLJ treated in a hospital in Mexico were reviewed, in the period 2018-2021. HPV was identied in all patients for genomes 6, 11, 16, and 18. nine patients were included, 56% women, mean age 9.5 ± 5.7 years; seven patients registered positivity for HPV-11 and 2 for HPV-6. The average age at diagnosis was 2.35 ± 1.77 years, with an average of 12 ± 11.56 surgical procedures. In conclusion, the most frequent genotypes in patients with PLJ were HPV-6 and HPV-11, with the latter predominating.

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