Data on transcriptome profiling of circulating microRNAs in dairy cattle
Kesavan Markkandan,
Hyun-joo Lim,
Dong Jin Lee,
In-gang Shin,
Seung-il Yoo,
Changgwon Dang,
Chang Pyo Hong,
Kung Ahn
Affiliations
Kesavan Markkandan
Theragen ETEX Bio Institute, Suwon, Gyeonggi-do 16229, Republic of Korea
Hyun-joo Lim
National Institute of Animal Science (NIAS), RDA, Cheonan 331-801, Republic of Korea
Dong Jin Lee
Theragen ETEX Bio Institute, Suwon, Gyeonggi-do 16229, Republic of Korea
In-gang Shin
Theragen ETEX Bio Institute, Suwon, Gyeonggi-do 16229, Republic of Korea
Seung-il Yoo
Theragen ETEX Bio Institute, Suwon, Gyeonggi-do 16229, Republic of Korea
Changgwon Dang
National Institute of Animal Science (NIAS), RDA, Cheonan 331-801, Republic of Korea
Chang Pyo Hong
Theragen ETEX Bio Institute, Suwon, Gyeonggi-do 16229, Republic of Korea
Kung Ahn
Theragen ETEX Bio Institute, Suwon, Gyeonggi-do 16229, Republic of Korea; Correspondence to: 2nd fl. AICT Bldg. B. 145 Gwanggyo-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do 16229, Republic of Korea.
MicroRNA (miRNA) are found in numerous biofluids including blood and are considered a new class of biomarkers. The data presented here are related to the research article entitled “Profiling and identification of pregnancy-associated circulating microRNAs in dairy cattle” (Markkandan et al. 2018). In the cited article, we sequenced the circulating microRNAs of the three healthy dairy cows of normal and 30 days of pregnancy (DOP) using Illumina RNA-Seq. Differentially expressed genes (DEG) analysis between normal and pregnant samples showed perturbations in miRNA expression. Herein, we made a comparison of DEGs at normal and 60 DOP libraries. The analysis results showed that 147 known miRNAs were differently expressed at 60 DOP groups when compared to the normal group. In addition, stage specific miRNAs were also predicted. Keywords: Circulating microRNA, Holstein, MiRNA-sequencing, Exosome, Pregnancy
