Are fewer cases of diabetes mellitus diagnosed in the months after SARS-CoV-2 infection? A population-level view in the EHR-based RECOVER program

Neha V. Reddy; Hsin-Chieh Yeh; Jena S. Tronieri; Til Stürmer; John B. Buse; Jane E. Reusch; Steven G. Johnson; Rachel Wong; Richard Moffitt; Kenneth J. Wilkins; Jeremy Harper; Carolyn T. Bramante; the N3C and RECOVER Consortiums

doi:10.1017/cts.2023.34

Journal of Clinical and Translational Science (Jan 2023)

Are fewer cases of diabetes mellitus diagnosed in the months after SARS-CoV-2 infection? A population-level view in the EHR-based RECOVER program

Neha V. Reddy,
Hsin-Chieh Yeh,
Jena S. Tronieri,
Til Stürmer,
John B. Buse,
Jane E. Reusch,
Steven G. Johnson,
Rachel Wong,
Richard Moffitt,
Kenneth J. Wilkins,
Jeremy Harper,
Carolyn T. Bramante,
the N3C and RECOVER Consortiums

Affiliations

Neha V. Reddy: ORCiD; Division of General Internal Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA
Hsin-Chieh Yeh: Departments of Medicine, Epidemiology and Oncology, Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, MD, USA
Jena S. Tronieri: Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
Til Stürmer: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
John B. Buse: ORCiD; Division of Endocrinology, Department of Medicine, University of North Carolina Medical School, Chapel Hill, NC, USA
Jane E. Reusch: University of Colorado Denver Anschutz Medical Campus, Denver, CO, USA
Steven G. Johnson: Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA
Rachel Wong: Department of Biomedical Informatics, Stony Brook University, Stony Brook, NY, USA
Richard Moffitt: Department of Biomedical Informatics, Stony Brook University, Stony Brook, NY, USA
Kenneth J. Wilkins: Biostatistics Program, Office of the Director, National Institute of Diabetes and Digestive and Kidney Disease, Bethesda, MD, USA
Jeremy Harper: Owl HealthWorks, Indianapolis, IN, USA
Carolyn T. Bramante: Division of General Internal Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA
the N3C and RECOVER Consortiums

DOI: https://doi.org/10.1017/cts.2023.34
Journal volume & issue: Vol. 7

Abstract

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Long-term sequelae of severe acute respiratory coronavirus-2 (SARS-CoV-2) infection may include increased incidence of diabetes. Here we describe the temporal relationship between new type 2 diabetes and SARS-CoV-2 infection in a nationwide database. We found that while the proportion of newly diagnosed type 2 diabetes increased during the acute period of SARS-CoV-2 infection, the mean proportion of new diabetes cases in the 6 months post-infection was about 83% lower than the 6 months preinfection. These results underscore the need for further investigation to understand the timing of new diabetes after COVID-19, etiology, screening, and treatment strategies.

Published in Journal of Clinical and Translational Science

ISSN: 2059-8661 (Online)
Publisher: Cambridge University Press
Country of publisher: United Kingdom
LCC subjects: Medicine
Website: https://www.cambridge.org/core/journals/journal-of-clinical-and-translational-science

About the journal

Abstract

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