Nature Communications (Apr 2022)

Molecular basis of antibiotic self-resistance in a bee larvae pathogen

  • Tam Dang,
  • Bernhard Loll,
  • Sebastian Müller,
  • Ranko Skobalj,
  • Julia Ebeling,
  • Timur Bulatov,
  • Sebastian Gensel,
  • Josefine Göbel,
  • Markus C. Wahl,
  • Elke Genersch,
  • Andi Mainz,
  • Roderich D. Süssmuth

DOI
https://doi.org/10.1038/s41467-022-29829-w
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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The authors show that the N-acetyltransferase PamZ acts as a self-resistance factor disabling the antibacterial paenilamicin that is produced by the honey bee larvae pathogen Paenibacillus larvae.