Higher arterial pressure during cardiopulmonary bypass may not reduce the risk of acute kidney injury

Abstract

Abstract Background Acute kidney injury after cardiac surgery is common and associated with increased mortality. It is unknown whether an intended higher arterial pressure during cardiopulmonary bypass reduces the incidence of acute and chronic kidney injury. Methods Patients were randomised either to a control group or a high pressure group (arterial pressure > 60 mmHg). The inclusion criteria were age > 70 years, combined cardiac surgery and serum creatinine 60 mmHg did not decrease the incidence of acute or chronic kidney injury after cardiac surgery. Trial registration Clinicaltrials.gov, identifier: NCT01408420. Registered 3rd of August 2011.

Keywords

• Acute kidney injury
• Arterial pressure
• Cardiac surgery