S198: BET INHIBITOR PELABRESIB (CPI-0610) COMBINED WITH RUXOLITINIB IN PATIENTS WITH MYELOFIBROSIS — JAK INHIBITOR-NAÏVE OR WITH SUBOPTIMAL RESPONSE TO RUXOLITINIB — PRELIMINARY DATA FROM THE MANIFEST STUDY

• J. Mascarenhas,
• M. Kremyanskaya,
• A. Patriarca,
• C. Harrison,
• P. Bose,
• R. K. Rampal,
• F Palandri,
• T. Devos,
• F. Passamonti,
• G. Hobbs,
• M. Talpaz,
• A. Vannucchi,
• J.-J. Kiladjian,
• S. Verstovsek,
• R. Hoffman,
• M. E. Salama,
• D. Chen,
• P. Taverna,
• A. Chang,
• G. Colak,
• S. Klein,
• V. Gupta

Affiliations

J. Mascarenhas

1 Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America

M. Kremyanskaya

1 Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America

A. Patriarca

2 Hematology Unit, Department of Translational Medicine, University of Eastern Piedmont and AOU Maggiore della Carità, Novara, Italy

C. Harrison

3 Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom

P. Bose

4 MD Anderson Cancer Center, Houston, TX

R. K. Rampal

5 Memorial Sloan-Kettering Cancer Center, New York, NY, United States of America

F Palandri

6 IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia “Seràgnoli”, Bologna, Italy

T. Devos

7 University Hospitals Leuven and Laboratory of Molecular Immunology (Rega Institute), KU Leuven, Leuven, Belgium

F. Passamonti

8 University of Insubria, Varese, Italy

G. Hobbs

9 Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

M. Talpaz

10 University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, United States of America

A. Vannucchi

11 Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy

J.-J. Kiladjian

12 Hôpital Saint-Louis, Université de Paris, Paris, France

S. Verstovsek

13 Leukemia Department, University of Texas MD Anderson Cancer Center, Houston, TX

R. Hoffman

1 Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America

M. E. Salama

13 Leukemia Department, University of Texas MD Anderson Cancer Center, Houston, TX

D. Chen

14 Mayo Clinic, Rochester, MN

P. Taverna

15 Constellation Pharmaceuticals a MorphoSys Company, Boston, MA, United States of America

A. Chang

15 Constellation Pharmaceuticals a MorphoSys Company, Boston, MA, United States of America

G. Colak

15 Constellation Pharmaceuticals a MorphoSys Company, Boston, MA, United States of America

S. Klein

15 Constellation Pharmaceuticals a MorphoSys Company, Boston, MA, United States of America

V. Gupta

16 Princess Margaret Cancer Centre, University of Toronto, Toronto, Canada