First Stereoselective Total Synthesis of Marliolide-(4R,5R,3E)‑4-hydroxy-5-methyl-3-tetradecylidenedihydrofuran-2(3H)‑one and Vittarilide-B: A Unified Strategy Utilizing a Chiral Pool Approach

• Janardana Reddi Desireddi,
• Mora Mallikarjuna Rao,
• Kiran Kumar Murahari,
• Shivanagababu Challa,
• Bhimcharan Maiti,
• Ravinder Manchal

Affiliations

Janardana Reddi Desireddi

Medicinal Chemistry Division, Aragen Life Sciences Pvt Limited, Hyderabad, Telangana, India

Mora Mallikarjuna Rao

Process Research and Development Department, Sai Lifesciences Limited, Hyderabad, Telangana, India

Kiran Kumar Murahari

Medicinal Chemistry Division, Aragen Life Sciences Pvt Limited, Hyderabad, Telangana, India

Shivanagababu Challa

Department of Chemistry, Georgia State University, Atlanta, Georgia, United States

Bhimcharan Maiti

Medicinal Chemistry Division, Aragen Life Sciences Pvt Limited, Hyderabad, Telangana, India

Ravinder Manchal

Department of Chemistry, Chaitanya (Deemed to be University), Hyderabad, Telangana, India