Association of genetic polymorphisms of brain natriuretic peptide with cardiovascular diseases

Abstract

Currently, natriuretic peptides (including brain natriuretic peptide (BNP)) are widely used in clinical practice as biomarkers for various cardiovascular diseases. Study of the structure and function of NPPA-NPPB locus can help to better identify patients at risk of future cardiovascular diseases, in particular heart failure.

Keywords

• genetic polymorphisms
• natriuretic peptide
• brain natriuretic peptide
• n-terminal pro-brain natriuretic peptide
• genetic markers