Hemophagocytic lymphohistiocytosis associated with anaplasmosis

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome characterized by unregulated macrophage and T-lymphocyte activation resulting in cytokine overproduction and subsequent histiocytic phagocytosis. Variant infections, particularly viruses have been postulated as the inciting factor for this potentially fatal disease. Herein, we will report a case of HLH associated with anaplasmosis.

Keywords

• Anaplasmosis
• hemophagocytic lymphohistiocytosis
• hemophagocytic syndrome