Pulmonary lymphatic function and its research progress in pulmonary diseases
Kang Xuya,
Fang Ran,
Zhang Yan,
Liu Yahan,
Dong Erdan
Affiliations
Kang Xuya
Institute of Cardiovascular Sciences, Peking University, Beijing 100191, China; State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing 100191, China
Fang Ran
Institute of Cardiovascular Sciences, Peking University, Beijing 100191, China; State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing 100191, China
Zhang Yan
Institute of Cardiovascular Sciences, Peking University, Beijing 100191, China; State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing 100191, China
Liu Yahan
Institute of Cardiovascular Sciences, Peking University, Beijing 100191, China; State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing 100191, China
Dong Erdan
State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing 100191, China; Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Research Unit of Medical Science Research Management/Basic and Clinical Research of Metabolic Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing 100191, China; Research Center of Population Health and Social Development, University of Health and Rehabilitation Sciences/Soft Science Research Base of Public Policy on Population Health in Shandong Province, Qingdao 266071, Shandong, China
The lymphatic system is a unidirectional network in which lymph fluid flows centripetally along a series of lymphatic channels and eventually into the veins, so the lymphatic system can also be considered an auxiliary part of the venous system and an important part of the cardiovascular system. The lymphatic system, which regulates interstitial fluid balance, lipid absorption, and immune monitoring, and its imbalance can lead to a variety of diseases. The pulmonary lymphatic system plays a very important role in many lung diseases, involving maintaining fluid balance, antigen presentation, etc., in addition, it will affect the survival of the transplant after lung transplantation. This article focuses on pulmonary lymphatic vessels and their role in lung disease.