Revista do Instituto de Medicina Tropical de São Paulo (Feb 2006)

Distribution of hepatitis C virus genotypes among blood donors from mid-west region of Brazil

  • Regina M.B. Martins,
  • Sheila A. Teles,
  • Nara R. Freitas,
  • Ana R.C. Motta-Castro,
  • Francisco J.D. Souto,
  • Aparecida Mussi,
  • Regina M.S. Amorim,
  • Cláudia R.F. Martins

Journal volume & issue
Vol. 48, no. 1
pp. 53 – 55

Abstract

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In order to investigate the hepatitis C virus (HCV) genotypes in mid-west region of Brazil, 250 anti-HCV positive blood donors were studied. Among them, the anti-HCV serological status was confirmed in 205 (82%). HCV RNA was detected in 165 samples, which were genotyped. HCV types 1, 2 and 3 were found in 67.9%, 3% and 29.1% of the donors, respectively. In Goiás state, subtype 1a (50%) was the most prevalent, followed by subtypes 3a (30.9%) and 1b (16.7%). In Mato Grosso state, subtype 1a was also predominant (41%), followed by subtypes 1b (29.5%) and 3a (25%). In Mato Grosso do Sul state, subtypes 1a and 1b were detected equally (36.8%), followed by 3a (21.1%). Subtype 2b was rare (2.4%, 4.5% and 5.3%, respectively). In Distrito Federal, subtype 3a (39%) was more frequent than 1a (31.7%) and the remaining (29.3%) belonged to subtype 1b.

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