Incidental Finding of Gall Bladder Carcinoma in Post-Menopausal Females in Cholecystectomy Specimen

Abstract

Objective: To highlight the significance of histopathological examination of gallbladder and to evaluate incidental gallbladder cancer in post-menopausal females. Study Design: Cross-sectional Study. Place and Duration of Study: Department of Pathology, Diagnostic and Research Laboratory, Liaquat University of Medical and Health Sciences, Hyderabad Pakistan, from Jan 2020 to Dec 2021. Methodology: Two thousand nine hundred fifty-nine (n=2959) gallbladder specimens with a clinical diagnosis of cholelithiasis and cholecystitis were analyzed. The clinical history of patients was taken from computer storage data. Results: Out of the total 2959 cases, on histopathological examination, chronic cholecystitis was the commonest finding (1990, 67.25%), followed by acute cholecystitis 410(13.85%) cholesterolosis (396,13.38%) and gallbladder carcinoma 42(1.42%). Out of 42 cases of gallbladder carcinoma, 34(80.95%) were female and 8(19%) were male. Most cases were post-menopausal age group 21(61.76%) compared to premenopausal 13(38.23%). Conclusion: In our study, Incidental gallbladder carcinoma in post-menopausal women was higher than expected.

Keywords

• Cholecystectomy
• Cholelithiasis
• Gall bladder carcinoma
• Post-menopausal females