Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits

J. Fernández-Sevillano; A. González-Pinto; J. Rodríguez-Revuelta; S. Alberich-Mesa; L. González-Blanco; I. Zorrilla-Martínez; Á. Velasco; P. López-Pena; I. Abad-Acebedo; P.A. Saiz

doi:10.1192/j.eurpsy.2021.1558

European Psychiatry (Apr 2021)

Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits

J. Fernández-Sevillano,
A. González-Pinto,
J. Rodríguez-Revuelta,
S. Alberich-Mesa,
L. González-Blanco,
I. Zorrilla-Martínez,
Á. Velasco,
P. López-Pena,
I. Abad-Acebedo,
P.A. Saiz

Affiliations

J. Fernández-Sevillano: Medicine Department, Neuroscience, University of the Basque Country, LEIOA, Spain Bipolar Disorder Research Group, CIBERSAM, Madrid, Spain Department Of Psychiatry, Araba University Hospital, BIOARABA RESEARCH INSTITUTE Osakidetza Basque Health Service, Araba University Hospital, Vitoria-Gasteiz, Spain
A. González-Pinto: Bipolar Disorder Research Group, CIBERSAM, Madrid, Spain Medicine Departament, Neuroscience, University of the Basque Country, LEIOA, Spain Departametn Of Psychiatry, Araba University Hospital, BIOARABA RESEARCH INSTITUTE Osakidetza Basque Health Service, Araba University Hospital, Vitoria-Gasteiz, Spain
J. Rodríguez-Revuelta: Department Of Psychiatry, University of Oviedo, Oviedo, Spain Neuroscience And Sense Organs, ISPA HEALTH RESEARCH INSTITUTE OF THE PRINCIPALITY OF ASTURIAS, Oviedo, Spain Psychiatry, SESPA Mental Health Services of Principado de Asturias, OVIEDO, Spain
S. Alberich-Mesa: Bipolar Disorder Research Group, CIBERSAM, Madrid, Spain Department Of Psychiatry, Araba University Hospital, BIOARABA RESEARCH INSTITUTE Osakidetza Basque Health Service, Araba University Hospital, Vitoria-Gasteiz, Spain
L. González-Blanco: Bipolar Disorder Research Group, CIBERSAM, Madrid, Spain Department Of Psychiatry, University of Oviedo, Oviedo, Spain Neuroscience And Sense Organs, ISPA HEALTH RESEARCH INSTITUTE OF THE PRINCIPALITY OF ASTURIAS, Oviedo, Spain Psychiatry, SESPA Mental Health Services of Principado de Asturias, OVIEDO, Spain
I. Zorrilla-Martínez: Medicine Department, Neuroscience, University of the Basque Country, LEIOA, Spain Bipolar Disorder Research Group, CIBERSAM, Madrid, Spain Department Of Psychiatry, Araba University Hospital, BIOARABA RESEARCH INSTITUTE Osakidetza Basque Health Service, Araba University Hospital, Vitoria-Gasteiz, Spain
Á. Velasco: Department Of Psychiatry, University of Oviedo, Oviedo, Spain Neuroscience And Sense Organs, ISPA HEALTH RESEARCH INSTITUTE OF THE PRINCIPALITY OF ASTURIAS, Oviedo, Spain Psychiatry, SESPA Mental Health Services of Principado de Asturias, OVIEDO, Spain
P. López-Pena: Medicine Department, Neuroscience, University of the Basque Country, LEIOA, Spain Bipolar Disorder Research Group, CIBERSAM, Madrid, Spain Department Of Psychiatry, Araba University Hospital, BIOARABA RESEARCH INSTITUTE Osakidetza Basque Health Service, Araba University Hospital, Vitoria-Gasteiz, Spain
I. Abad-Acebedo: Department Of Psychiatry, University of Oviedo, Oviedo, Spain
P.A. Saiz: Department Of Psychiatry, University of Oviedo, Oviedo, Spain Neuroscience And Sense Organs, ISPA HEALTH RESEARCH INSTITUTE OF THE PRINCIPALITY OF ASTURIAS, Oviedo, Spain Psychiatry, SESPA Mental Health Services of Principado de Asturias, OVIEDO, Spain Psychiatry, CIBERSAM, Madrid, Spain

DOI: https://doi.org/10.1192/j.eurpsy.2021.1558
Journal volume & issue: Vol. 64
pp. S584 – S584

Abstract

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Introduction Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits Introduction: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological alterations could lead to difficulties in interpreting and managing life events resulting in a higher risk of suicide. Objectives Objective: Bibliographic review about the influence of neuropsychological deficits on suicidal behaviour. Methods Method: A systematic literature search from 2000 to 2020 was performed in Medline (Pubmed), Web of Science, SciELO Citation Index, PsycInfo, PsycArticles and Cochrane Library databases regarding studies comparing cognition of attempters versus non-attempters that share same psychiatric diagnosis. Results: 1.885 patients diagnosed with an Affective Disorder (n = 1512) and Schizophrenia/ Schizoaffective Disorder (n = 373) were included. Results In general comparison, attention was found to be clearly dysfunctional. Regarding diagnosis, patients with Schizophrenia and previous history of suicidal behaviour showed a poorer performance in executive function. Patients with current symptoms of an Affective Disorder and a previous history of suicidal attempt had poorer performance in attention and executive function. Similarly, euthymic affective patients with history of suicidal behaviour had worse decision-making, attention and executive function performance compared to euthymic non-attempters. Conclusions Patients who have attempted suicide have a poorer neuropsychological functioning than non-attempters with a similar psychiatric disorder in attention and executive function. These alterations increase vulnerability for suicide. Conflict of interest Jessica Fernández-Sevillano is beneficiary of the Pre-PhD Training Programme of the Basque Government. Dr. Gonzalez-Pinto has received grants and served as consultant, advisor or CME speaker for the following entities: Almirall, AstraZeneca, Bristol-Myers

Published in European Psychiatry

ISSN: 0924-9338 (Print); 1778-3585 (Online)
Publisher: Cambridge University Press
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system: Psychiatry
Website: https://www.cambridge.org/core/journals/european-psychiatry

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