Терапевтический архив (Oct 2016)

Ovarian reserve and adipokine levels in reproductive-aged obese women

  • A K Durmanova,
  • N K Otarbayev,
  • A Kaiyrlykyzy,
  • K Kh Zhangazieva,
  • Zh N Ibrayeva,
  • G B Donenbayeva,
  • Zh T Zhusupova,
  • А S Saidakhmetov,
  • G Sh Temirgaliyeva,
  • Zh K Salykbayeva,
  • Zh M Tazhigulova,
  • А M Yensebayeva,
  • К K Seksembayeva,
  • О K Vasilenko,
  • S Timanova,
  • B Akkozhina

DOI
https://doi.org/10.17116/terarkh2016881046-50
Journal volume & issue
Vol. 88, no. 10
pp. 46 – 50

Abstract

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Aim. To investigate the relationship of the ovarian reserve to the levels of adipokines and sex hormones in reproductive-aged women with abdominal obesity. Subjects and methods. A total of 157 women aged 18 to 45 years with a body mass index (BMI) of more than 30 kg/m2 were examined (a study group). A control group consisted of 93 women aged 18—45 years with a BMI of less than 25 kg/m2. Anthropometric and carbohydrate and lipid metabolic parameters and the levels of sex hormones, anti-Müllerian hormone, resistin, and adiponectin were investigated. Results. The mean age of the participants with a BMI of more than 30 kg/m2 was 33.1±6.1 years and that of those with a BMI of less than 25—30 kg/m2 was 32.8±6.2 years. No statistically significant differences were found in age, ethnicity, and marital status between the participants of both groups; however, there was a statistically significant difference in education levels — 76.3% of the women with a BMI of less than 25 kg/m2 (p

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