Concomitant primary hyperparathyroidism and systemic lupus erythematosus: coincidence or not? A new case report

Abstract

Primary hyperparathyroidism (PHP) is the most common causes of hypercalcemia. Patients with systemic lupus erythematosus (SLE) can develop hypercalcemia but it is exceptionally due to PHP. There is only few cases of Concurrent SLE and primary hyperparathyroidism (PHP) described in the literature. We report a case of 31-year-old patient having SLE with lupus nephritis class III and anti-phospholipid syndrom, complicated by pulmonary embolism associated to primary hyperparathyroidism causing severe hypercalcemia, and osteoporosis. Even if there is no evidence for potential pathogenic association between PHP and SLE, the recognition of this association is very important because of therapeutic and prognostic impact. Early detection of PHP leads to avoid severe complications and significant morbidity.

Keywords

• hypercalcemia
• primary hyperparathyroidism
• systemic lupus erythematosus
• case report