Communications Biology (Apr 2022)
CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue
- Job van Riet,
- Chinmoy Saha,
- Nikolaos Strepis,
- Rutger W. W. Brouwer,
- Elena S. Martens-Uzunova,
- Wesley S. van de Geer,
- Sigrid M. A. Swagemakers,
- Andrew Stubbs,
- Yassir Halimi,
- Sanne Voogd,
- Arif Mohammad Tanmoy,
- Malgorzata A. Komor,
- Youri Hoogstrate,
- Bart Janssen,
- Remond J. A. Fijneman,
- Yashar S. Niknafs,
- Arul M. Chinnaiyan,
- Wilfred F. J. van IJcken,
- Peter J. van der Spek,
- Guido Jenster,
- Rogier Louwen
Affiliations
- Job van Riet
- Department of Urology, Erasmus MC Cancer Institute, University Medical Center Rotterdam
- Chinmoy Saha
- Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam
- Nikolaos Strepis
- Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam
- Rutger W. W. Brouwer
- Center for Biomics, Erasmus University Medical Center Rotterdam
- Elena S. Martens-Uzunova
- Department of Urology, Erasmus MC Cancer Institute, University Medical Center Rotterdam
- Wesley S. van de Geer
- Cancer Computational Biology Center, Erasmus MC Cancer Institute, University Medical Center Rotterdam
- Sigrid M. A. Swagemakers
- Clinical Bioinformatics, Department of Pathology, Erasmus University Medical Center Rotterdam
- Andrew Stubbs
- Clinical Bioinformatics, Department of Pathology, Erasmus University Medical Center Rotterdam
- Yassir Halimi
- Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam
- Sanne Voogd
- Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam
- Arif Mohammad Tanmoy
- Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam
- Malgorzata A. Komor
- Translational Gastrointestinal Oncology, Department of Pathology, Netherlands Cancer Institute
- Youri Hoogstrate
- Department of Neurology, Erasmus University Medical Center Rotterdam
- Bart Janssen
- GenomeScan
- Remond J. A. Fijneman
- Translational Gastrointestinal Oncology, Department of Pathology, Netherlands Cancer Institute
- Yashar S. Niknafs
- Michigan Center for Translational Pathology, University of Michigan
- Arul M. Chinnaiyan
- Michigan Center for Translational Pathology, University of Michigan
- Wilfred F. J. van IJcken
- Center for Biomics, Erasmus University Medical Center Rotterdam
- Peter J. van der Spek
- Clinical Bioinformatics, Department of Pathology, Erasmus University Medical Center Rotterdam
- Guido Jenster
- Department of Urology, Erasmus MC Cancer Institute, University Medical Center Rotterdam
- Rogier Louwen
- Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam
- DOI
- https://doi.org/10.1038/s42003-022-03249-4
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 13
Abstract
CRISPR elements in the human genome are expressed in both healthy tissues and tumors but with distinct patterns, representing a potential biomarker for cancer.
