Nature Communications (Dec 2019)

Multimodal image registration and connectivity analysis for integration of connectomic data from microscopy to MRI

  • Maged Goubran,
  • Christoph Leuze,
  • Brian Hsueh,
  • Markus Aswendt,
  • Li Ye,
  • Qiyuan Tian,
  • Michelle Y. Cheng,
  • Ailey Crow,
  • Gary K. Steinberg,
  • Jennifer A. McNab,
  • Karl Deisseroth,
  • Michael Zeineh

DOI
https://doi.org/10.1038/s41467-019-13374-0
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 17

Abstract

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Many approaches exist to process data from individual imaging modalities, but integrating them is challenging. The authors develop an automated resource that enables co-registered network- and tract-level analysis of macroscopic in-vivo imaging and microscopic imaging of cleared tissue.