Disease Models & Mechanisms (Nov 2024)
Early-life cisplatin exposure induces neuroinflammation and chemotherapy-induced neuropathic pain
- Marlene Da Vitoria Lobo,
- Lydia Hardowar,
- Tameille Valentine,
- Lucy Tomblin,
- Charlotte Guest,
- Dhyana Sharma,
- Benjamin Dickins,
- Mark Paul-Clark,
- Richard Philip Hulse
Affiliations
- Marlene Da Vitoria Lobo
- Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK
- Lydia Hardowar
- Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK
- Tameille Valentine
- Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK
- Lucy Tomblin
- Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK
- Charlotte Guest
- Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK
- Dhyana Sharma
- Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK
- Benjamin Dickins
- Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK
- Mark Paul-Clark
- Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK
- Richard Philip Hulse
- Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK
- DOI
- https://doi.org/10.1242/dmm.052062
- Journal volume & issue
-
Vol. 17,
no. 11
Abstract
No abstracts available.Keywords
- nociceptor
- dorsal root ganglia
- nerve growth factor
- chemotherapy
- cisplatin
- neurodegeneration
- trpv1
- inflammation
- macrophage
