Dimethyl 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Abstract

The title molecule, C17H19NO5, was prepared by a Hantzsch dihydropyridine synthesis from 4-hydroxybenzaldehyde, methyl acetoacetate and NH4HCO3. In the molecular structure of the title compound, the dihydropyridine ring adopts a flattened boat conformation and the plane of the base of the boat forms a dihedral angle of 80.8 (2)° with the aromatic six-membered ring. The packing is stabilized by strong intermolecular N—H...Ocarbonyl, Ohydroxy—H...Ocarbonyl and weak intramolecular C—H...O hydrogen bonds.