Asian Pacific Journal of Reproduction (Jan 2022)

Oxidative stress and female reproductive disorder: A review

  • Kalaivani Manokaran,
  • Pavithra Bhat,
  • Deepak Nayak,
  • Ravisankar Baskaran,
  • Prabu Paramasivam,
  • Shiek Fareeth Ahmed,
  • Keerthi Priya,
  • Karkala Sreedhara Ranganath Pai,
  • Vignesh E Balaji

DOI
https://doi.org/10.4103/2305-0500.346088
Journal volume & issue
Vol. 11, no. 3
pp. 107 – 116

Abstract

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Oxidative stress arises from an imbalance between the body’s pro-oxidants and antioxidants. Recently, oxidative stress has been proven a contributing factor to many female reproductive disorders including infertility, preeclampsia, endometriosis and polycystic ovarian syndrome. Herein, we review the mechanistic role of oxidative stress in inducing the most common female reproductive disorders. The current review has also highlighted the protective role of vitamin C, necessary for certain female reproductive hormone secretion by the antral follicle and corpus luteum and also essential for collagen production in ovarian tissue remodeling after ovulation, in alleviating oxidative stress and thus improving female reproductive outcomes.

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