Cell Reports: Methods (Nov 2023)

Third-generation rabies viral vectors have low toxicity and improved efficiency as retrograde labeling tools

  • Lindsay A. Schwarz

Journal volume & issue
Vol. 3, no. 11
p. 100646

Abstract

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In this issue of Cell Reports Methods, Jin et al. report the generation and validation of a rabies variant, RVΔL, for projection-based neuronal labeling. RVΔL shows little toxicity in vivo and has an improved growth advantage over another variant, RVΔGL, making it a useful tool for a wide variety of systems neuroscience-based studies.