Case Reports in Oncology (Nov 2022)

An Unusual Presentation of HCC in a Patient with No Underlying Liver Disease: A Case Study

  • Anton Osyntsov,
  • Melanie Zemel,
  • Nir Cohen,
  • Jonah M. Cooper,
  • Muhammad Krenawi,
  • Bilal Krayim,
  • Waleed Kian,
  • Ranin Marei,
  • Walid Shalata,
  • Gilbert Sebbag,
  • Shadi Abu-Swis

DOI
https://doi.org/10.1159/000526929
Journal volume & issue
Vol. 15, no. 3
pp. 995 – 1000

Abstract

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Pedunculated hepatocellular carcinoma (P-HCC) is a rare subtype of HCC. P-HCC may occur in patients without underlying liver cirrhosis and can be present with negative serum tumor markers. With a growing worldwide incidence of nonalcoholic fatty liver disease, non-cirrhotic HCC will likely become more prevalent. We report a patient presenting to the hospital with nonspecific symptoms of weight loss, abdominal discomfort, and early satiety. Abdomen palpation found a large firm mass in the right middle abdomen. Computed tomography imaging showed a large right abdominal mass without evidence of liver attachment. The patient underwent a diagnostic laparotomy where a single 17 cm exophytic mass originating from the left liver lobe was found and resected. Clear margins were attained, and pathology demonstrated HCC. Early diagnosis of HCC is critical to achieving curative treatment, and physicians should keep P-HCC in mind when presented with a similar patient.

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