Dysbiosis and Intestinal Permeability: Causes and Effects of Altering Normal Intestinal Flora

Abstract

Abstract Introduction: The balance of the microbiota is determined by the high diversity and its ability to withstand changes under physiological stress, therefore, its health parameters are the number of microorganisms and the variety of bacterial species. The decrease in the number of microorganisms or species, reduces immunity as it relates to diseases of the gastrointestinal tract that result in producing systemic alterations. Objective: To know the different effects of the alteration of the normal intestinal flora in the human body. Method: Systematic literature review in search engines: LILACS, CINAHL, COCHRANE, EBSCO, MEDLINE, SCIELO, SCOPUS and PUBMED, using terms such as microbiota, dysbiosis, alteration of intestinal flora, among others. Results: Review of 40 articles from the last five years and including 30 that are related to the subject and objective of the present literature review study. Discussion: Bacterial dysbiosis causing alterations in the organism that lead to different pathologies. Conclusion: Dysbiosis or dysbacteria is of great importance in humans, since its alteration causes endless changes, even altering its normal functioning, causing pathologies, that a simple view would be ruled out as a consequence of the alteration of the bacterial flora.