Interactions between the WEE-1.3 kinase and the PAM-1 aminopeptidase in oocyte maturation and the early <i>C. elegans</i> embryo

Dorothy Benton; Eva C Jaeger; Arielle Kilner; Ashley Kimble; Josh Lowry; Emily M Schleicher; Kaiden M Power; Danielle Uibel; Caprice Eisele; Bruce Bowerman; Rebecca Lyczak

doi:10.1093/g3journal/jkab063

G3: Genes, Genomes, Genetics (Mar 2021)

Interactions between the WEE-1.3 kinase and the PAM-1 aminopeptidase in oocyte maturation and the early <i>C. elegans</i> embryo

Dorothy Benton,
Eva C Jaeger,
Arielle Kilner,
Ashley Kimble,
Josh Lowry,
Emily M Schleicher,
Kaiden M Power,
Danielle Uibel,
Caprice Eisele,
Bruce Bowerman,
Rebecca Lyczak

Affiliations

Dorothy Benton: Biology Department, Ursinus College, 601 E Main Street, Collegeville, PA 19426, USA
Eva C Jaeger: Biology Department, Ursinus College, 601 E Main Street, Collegeville, PA 19426, USA
Arielle Kilner: Biology Department, Ursinus College, 601 E Main Street, Collegeville, PA 19426, USA
Ashley Kimble: Biology Department, Ursinus College, 601 E Main Street, Collegeville, PA 19426, USA
Josh Lowry: Institute of Molecular Biology, 1229 University of Oregon, 1318 Franklin Blvd., Eugene, OR 97403, USA
Emily M Schleicher: Biology Department, Ursinus College, 601 E Main Street, Collegeville, PA 19426, USA
Kaiden M Power: ORCiD; Biology Department, Ursinus College, 601 E Main Street, Collegeville, PA 19426, USA
Danielle Uibel: Biology Department, Ursinus College, 601 E Main Street, Collegeville, PA 19426, USA
Caprice Eisele: Biology Department, Ursinus College, 601 E Main Street, Collegeville, PA 19426, USA
Bruce Bowerman: ORCiD; Institute of Molecular Biology, 1229 University of Oregon, 1318 Franklin Blvd., Eugene, OR 97403, USA
Rebecca Lyczak: Biology Department, Ursinus College, 601 E Main Street, Collegeville, PA 19426, USA

DOI: https://doi.org/10.1093/g3journal/jkab063
Journal volume & issue: Vol. 11, no. 4

Abstract

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AbstractPuromycin-sensitive aminopeptidases are found across phyla and are known to regulate the cell-cycle and play a protective role in neurodegenerative disease. PAM-1 is a puromycin-sensitive aminopeptidase important for meiotic exit and polarity establishment in the one-cell Caenorhabditis eleganspam-1wee-1.3pam-1wee-1.3pam-1pam-1

Published in G3: Genes, Genomes, Genetics

ISSN: 2160-1836 (Online)
Publisher: Oxford University Press
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General): Genetics
Website: https://academic.oup.com/g3journal

About the journal