EXPERIENCE OF TREATING MULTIPLE AND EXTENSIVE DRUG RESISTANT TUBERCULOSIS WITH NEW REGIMENS IN BELARUS REPUBLIC

Abstract

The objective of the study: to describe the efficiency and safety of new anti-tuberculosis drugs when treating tuberculosis patients with drug resistance.Subjects and methods. In Belarus, the retrospective and prospective analyses were performed in the cohort of 300 patients with multiple drug resistance and high rates of extensive drug resistance, who were treated with new drugs and drugs which were started to be used for the treatment of tuberculosis. In order to describe the cohort, blocks of variables were used to specify the efficiency and safety profiles of new anti-tuberculosis drugs.Results of the study. The high level of therapeutic efficiency of new regimens and their fairly favorable safety profile were demonstrated in the cohort.

Keywords

• туберкулез с множественной и широкой лекарственной устойчивостью возбудителя
• новые противотуберкулезные препараты
• профиль эффективности и безопасности
• бедаквилин