Journal of Obesity & Metabolic Syndrome (Jun 2020)
Current Long-Term Pharmacotherapies for the Management of Obesity
- Bo-Yeon Kim,
- Seon Mee Kang,
- Jee-Hyun Kang,
- Kyoung Kon Kim,
- Bomtaeck Kim,
- Seung Jun Kim,
- Yang-Hyun Kim,
- Jung-Hwan Kim,
- Jae Hyun Kim,
- Ga Eun Nam,
- Ji Yeon Park,
- Jang Won Son,
- Hye-Jung Shin,
- Tae Jung Oh,
- Hyug Lee,
- Eon-Ju Jeon,
- Sochung Chung,
- Yong Hee Hong,
- Chong Hwa Kim,
- Committee of Clinical Practice Guidelines, Korean Society for the Study of Obesity (KSSO)
Affiliations
- Bo-Yeon Kim
- Division of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea
- Seon Mee Kang
- Division of Endocrinology and Metabolism, Department of Internal Medicine, Sun Medical Center, Daejeon, Korea
- Jee-Hyun Kang
- Department of Family Medicine, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea
- Kyoung Kon Kim
- Department of Family Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea
- Bomtaeck Kim
- Department of Family Practice and Community Health, Ajou University Medical Center, Suwon, Korea
- Seung Jun Kim
- Department of Psychiatry, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea
- Yang-Hyun Kim
- Department of Family Medicine, Korea University College of Medicine, Seoul, Korea
- Jung-Hwan Kim
- Department of Family Medicine, Eulji Hospital, Eulji University School of Medicine, Seoul, Korea
- Jae Hyun Kim
- Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
- Ga Eun Nam
- Department of Family Medicine, Korea University College of Medicine, Seoul, Korea
- Ji Yeon Park
- Department of Surgery, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, Korea
- Jang Won Son
- Division of Endocrinology and Metabolism, Department of Internal Medicine, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Bucheon, Korea
- Hye-Jung Shin
- Department of Pediatrics, National Medical Center, Seoul, Korea
- Tae Jung Oh
- Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
- Hyug Lee
- Central St’ Mary’s Clinic Internal Medicine, Seoul, Korea
- Eon-Ju Jeon
- Division of Endocrinology and Metabolism, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea
- Sochung Chung
- Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
- Yong Hee Hong
- Department of Pediatrics, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea
- Chong Hwa Kim
- Division of Endocrinology and Metabolism, Department of Internal Medicine, Sejong General Hospital, Bucheon, Korea
- Committee of Clinical Practice Guidelines, Korean Society for the Study of Obesity (KSSO)
- DOI
- https://doi.org/10.7570/jomes20010
- Journal volume & issue
-
Vol. 29,
no. 2
pp. 99 – 109
Abstract
Obesity is a serious and growing worldwide health challenge associated with type 2 diabetes mellitus, cardiovascular disease, osteoarthritis, some cancers, sleep apnea, asthma, and nonalcoholic fatty liver. The Korean Society for the Study of Obesity recommends that pharmacotherapy should be considered when intensive lifestyle modifications fail to achieve a weight reduction in obese patients with a body mass index ≥25 kg/m². Long-term medications for obesity have traditionally fallen into two major categories: centrally acting anorexiant medications and peripherally acting medications, such as orlistat. In this paper, we provide an overview of the anti-obesity medications currently available for the long-term and individualized treatment of obesity.
Keywords
- obesity
- orlistat
- lorcaserin
- liraglutide
- naltrexone/bupropion extended-release
- phentermine/topiramate extended-release