Synthesis and Antiviral Activity of Hydrogenated Ferulic Acid Derivatives

Can Cui; Zhi-Peng Wang; Xiu-jiang Du; Li-Zhong Wang; Shu-Jing Yu; Xing-Hai Liu; Zheng-Ming Li; Wei-Guang Zhao

doi:10.1155/2013/269434

Journal of Chemistry (Jan 2013)

Synthesis and Antiviral Activity of Hydrogenated Ferulic Acid Derivatives

Can Cui,
Zhi-Peng Wang,
Xiu-jiang Du,
Li-Zhong Wang,
Shu-Jing Yu,
Xing-Hai Liu,
Zheng-Ming Li,
Wei-Guang Zhao

Affiliations

Can Cui: State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin 300071, China
Zhi-Peng Wang: State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin 300071, China
Xiu-jiang Du: State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin 300071, China
Li-Zhong Wang: State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin 300071, China
Shu-Jing Yu: State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin 300071, China
Xing-Hai Liu: College of Chemical Engineering & Materials Sciences, Zhejiang University of Technology, Hangzhou 310014, China
Zheng-Ming Li: State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin 300071, China
Wei-Guang Zhao: State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin 300071, China

DOI: https://doi.org/10.1155/2013/269434
Journal volume & issue: Vol. 2013

Abstract

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A series of hydrogenated ferulic acid amide derivatives 4 were synthesized. The molecular structures of the synthesized compounds were analyzed by H1 NMR and HRMS. The biological activity study showed that some of them displayed excellent protection activity and curative activity against TMV at 500 μg/mL.

Published in Journal of Chemistry

ISSN: 2090-9063 (Print); 2090-9071 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Science: Chemistry
Website: https://onlinelibrary.wiley.com/journal/2962

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