Materials Research Express (Jan 2024)

Vitis heyneana extract mediated synthesis of silver nanoparticles with high bioactive and colorimetric sensing properties

  • Pham Huong Quynh,
  • Tran Thi Thuy Ninh,
  • Nguyen Quang Tinh,
  • Nguyen Van Thu,
  • Dang Van Thanh,
  • Duc Dung Nguyen,
  • Cao Thanh Hai,
  • Khieu Thi Tam

DOI
https://doi.org/10.1088/2053-1591/ad5c2f
Journal volume & issue
Vol. 11, no. 7
p. 075002

Abstract

Read online

The green synthesis of inorganic nanoparticles using plant extracts has been an important strategy to mitigate the uses of hazardous chemicals and thus reduce toxic by-products. We herein report for the first time the synthesis of silver nanoparticles (AgNPs) utilizing Vitis heyneana fruit peel as a key agent. Specifically, oleanolic acid was found in the extract and its crucial role as both reducing and stabilizing agent was experimentally evidenced. The as-synthesized AgNPs were morphologically and structurally characterized to possess quasi-spherical shapes with an average diameter of 11 nm and exhibit polycrystalline nature. Bioactive studies indicated that as-synthesized AgNPs revealed potent antimicrobial activities against Lactobaccillus plantarum , Pseudomonas aeruginosa , and Aspergillus flavus, demonstrating an IC _50 value of 20.00 ± 2.05 μ g ml ^−1 and a MIC value of 32 ± 0.03 μ g ml ^−1 (against Pseudomonas aeruginosa ); the NPs also possessed superior antioxidant activities with an IC _50 value of 23.22 ± 1.25 μ g ml ^−1 compared to vitamin C (18.23 ± 0.15 μ g ml ^−1 ). The AgNPs further revealed capabilities of colorimetrically detecting Hg ^2+ ions with a limit of detection of 0.048 μ M and a limit of quantitation of 0.16 μ M. These findings therefore suggest promising uses of the phytosynthesized AgNPs in nanomedicine and sensing technology.

Keywords