Vestnik Transplantologii i Iskusstvennyh Organov (Jan 2019)

Lung transplantation for idiopathic pulmonary arterial hypertension: perioperational features

  • V. N. Poptsov,
  • E. A. Spirina,
  • I. V. Pashkov,
  • A. V. Belikova,
  • D. O. Oleshkevich,
  • R. A. Latipov,
  • O. M. Tsirulnikova,
  • A. C. Epremian,
  • E. F. Shigaev,
  • S. V. Gautier

DOI
https://doi.org/10.15825/1995-1191-2018-4-30-37
Journal volume & issue
Vol. 20, no. 4
pp. 30 – 37

Abstract

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Lung transplantation (LT) for idiopathic pulmonary arterial hypertension (IPAH) now is the only radical treatment of this disease.Aim: to analyze own experience of performing LT in patients with IPAH.Materials and methods. 8 adult IPAH patients, who underwent LT between 2014 and october 2018, were included. In 7 of 8 patients undergoing bilateral lung transplantation on intraoperative venoarterial extracorporeal membrane oxygenation (VA ECMO) with prolongation into the postoperative period.Results. VA ECMO support was prolonged into postoperative period 6 and 7 days respectively in 2 (25,0%) patients and 3 days in 6 (75,0%) patients. Hospital mortality in IPAH patients was 1.Conclusions. Own experience demonstrates that LT is an effective method of treatment in patients with IPAH. Hospital, 1- and 3-year survival rates for the patient collective were 87.5, 75.0 and 75.0% respectively.

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