Additive Effect of Dornase Alfa and Nacystelyn on Transportability and Viscoelasticity of Cystic Fibrosis Sputum

Feng Sun; Shusheng Tai; Thomas Lim; Ulrich Baumann; Malcolm King

doi:10.1155/2002/508942

Canadian Respiratory Journal (Jan 2002)

Additive Effect of Dornase Alfa and Nacystelyn on Transportability and Viscoelasticity of Cystic Fibrosis Sputum

Feng Sun,
Shusheng Tai,
Thomas Lim,
Ulrich Baumann,
Malcolm King

Affiliations

Feng Sun: Pulmonary Research Group, University of Alberta, Edmonton, Canada
Shusheng Tai: Pulmonary Research Group, University of Alberta, Edmonton, Canada
Thomas Lim: Pulmonary Research Group, University of Alberta, Edmonton, Canada
Ulrich Baumann: Department of Paediatric Pulmonology and Neonatology, , Hannover Medical School, Hannover, Germany
Malcolm King: Pulmonary Research Group, University of Alberta, Edmonton, Canada

DOI: https://doi.org/10.1155/2002/508942
Journal volume & issue: Vol. 9, no. 6
pp. 401 – 406

Abstract

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OBJECTIVE: To investigate the effect of dornase alfa (DA), Nacystelyn (NAL) and their combination on mucociliary transportability and mucus viscoelasticity of cystic fibrosis (CF) sputum, and to assess whether the combination possesses an additive effect.

Published in Canadian Respiratory Journal

ISSN: 1198-2241 (Print); 1916-7245 (Online)
Publisher: Hindawi Limited
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: https://www.hindawi.com/journals/crj/

About the journal