The Diagnostic Value of Multiparametric-MRI in Locating Prostate Cancer for Transrectal Ultrasound-Guided Biopsy

Abstract

Background and purpose: Prostate cancer is one of the most prevalent malignancies in men and its early detection contributes to the chance for a more sufficient treatment plan and a reduction in its complications. The usual methods for prostate cancer screening include serum PSA levels and digital rectal examination. In case the prostate cancer is suspected, transrectal ultrasound guided biopsy (TRUS) is performed as the gold standard for the diagnosis. The present study is designed to evaluate the potential efficacy of multiparametric-magnetic resonance imaging (mp-MRI) in detection of prostate cancer location. Materials and methods: a total of 66 subjects were participated in this cross sectional case-controlled study. Based on the results of the TRUS-guided biopsy, 33 of the participants had prostate cancer. All participants underwent MP-MRI imaging prior to the prostate biopsy. findings achieved by the either methods have been investigated and the comparison has been made. Results: It was revealed that the sensitivity and specificity of the mp-MRI in the diagnosis of prostate cancer were 81.8% and 93.9%, respectively. The positive and negative predictive value were 93.1% and 83.8%, respectively. Conclusion: The current study indicates that the mp-MRI imaging method has a sufficient sensitivity and specificity for detecting the location of prostate cancer and can potentially be employed as a clue-providing method prior to the TRUS-guided biopsy.

Keywords

• prostate cancer
• multiparametric MRI
• TRUS-guided biopsy