Molecules (Mar 2016)
In-Vitro Anticancer Evaluation of Some Novel Thioureido-Benzensulfonamide Derivatives
Abstract
A novel series of sulfonamide derivatives (14 compounds) bearing thiourea moieties were efficiently synthesized and evaluated for their possible in vitro anticancer activity against four human tumor cell lines. The results indicated that compound 6 was the most potent, showing effectiveness on all the tested cell lines. Compounds 7 and 10 also showed promising results.
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