Sagliker Syndrome in a Patient with Secondary Hyperparathyroidism and Chronic Renal Insufficiency: A Case Report

Abstract

Sagliker syndrome is a rare form of renal osteodystrophy resulted fromuntreated secondary hyperparathyroidism. It is described by severeskeletal deformities, high level of PTH in patients with chronic renalfailure, and deformed face. This paper reports a 44-year-old male patientwith the mentioned characteristics. In addition to the unique clinicalfeatures, high levels of ALP and PTH hormones encouraged us to searchfor syndrome-like a disease, which clinically and paraclinically matchedthe Sagliker syndrome.This case highlights the importance of clinicians’ attention for earlymonitoring and appropriate treatment as it is shown to be effectivein preventing irreversible complications such as soft tissue andbone abnormalities and cardiovascular impairment in patientswith Sagliker syndrome. Therefore, considering the syndrome isrecommended as one of the diagnostic hypothesis in young patientswith renal insufficiency, secondary hyperparathyroidism, and skeletaldeformities.

Keywords

• chronic renal failure
• renal osteodystrophy
• Sagliker syndrome
• secondary hyperparathyroidism
• skeletal deformity