442-B IL-18-enhanced non-activated CAR T-cells for improved metabolic function and therapeutic efficacy

• Carl H June,
• Joseph A Fraietta,
• Xiaoling Jin,
• Saba Ghassemi,
• Joseph Durgin,
• Ashwin Sannecy,
• Nandana Mukherjee,
• Andre Kelly,
• Alexander Shestov,
• Jakub Svoboda,
• Roddy O’Connor

Affiliations

Carl H June

3 Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

Joseph A Fraietta

1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Xiaoling Jin

1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Saba Ghassemi

1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Joseph Durgin

1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Ashwin Sannecy

1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Nandana Mukherjee

1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Andre Kelly

1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Alexander Shestov

1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

Jakub Svoboda

2Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA

Roddy O’Connor

1Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA