Lignans from the plant species Achillea lingulata

Abstract

Five lignans with a 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane skeleton, epieudesmin, kobusin, pinoresinol, fargesin and sesartemin, were isolated from the aerial parts and roots of Achillea lingulata. Their structures were identified by comparison of their 1H-NMR and MS data to those in the literature. Fargesin and pinoresinol have not been isolated previously from any species of the genus Achillea.

Keywords

• Asteraceae
• Achillea lingulata
• lignans
• epieudesmin
• kobusin
• pinoresinol
• fargesin
• sesartemin