mSphere (Feb 2021)
Molecular Evolution of Human Coronavirus 229E in Hong Kong and a Fatal COVID-19 Case Involving Coinfection with a Novel Human Coronavirus 229E Genogroup
- Susanna K. P. Lau,
- David C. Lung,
- Emily Y. M. Wong,
- Kam Leng Aw-Yong,
- Antonio C. P. Wong,
- Hayes K. H. Luk,
- Kenneth S. M. Li,
- Joshua Fung,
- Tony T. Y. Chan,
- James Y. M. Tang,
- Longchao Zhu,
- Cyril C. Y. Yip,
- Sally C. Y. Wong,
- Rodney A. Lee,
- Owen T. Y. Tsang,
- Kwok-Yung Yuen,
- Patrick C. Y. Woo
Affiliations
- Susanna K. P. Lau
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- David C. Lung
- Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China
- Emily Y. M. Wong
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Kam Leng Aw-Yong
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Antonio C. P. Wong
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Hayes K. H. Luk
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Kenneth S. M. Li
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Joshua Fung
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Tony T. Y. Chan
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- James Y. M. Tang
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Longchao Zhu
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Cyril C. Y. Yip
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Sally C. Y. Wong
- Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China
- Rodney A. Lee
- Department of Pathology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China
- Owen T. Y. Tsang
- Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, China
- Kwok-Yung Yuen
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- Patrick C. Y. Woo
- ORCiD
- Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
- DOI
- https://doi.org/10.1128/mSphere.00819-20
- Journal volume & issue
-
Vol. 6,
no. 1
Abstract
Since its first appearance in the 1960s, the genetic diversity and evolution of human coronavirus 229E (HCoV-229E) have been relatively understudied. In this study, we report a fatal case of COVID-19 coinfected with HCoV-229E in Hong Kong.
