Interaction between parental myopia and children lifestyle on the incidence of myopia among children aged 6–18 years: a cross-sectional study in Tianjin, China
Jing Yang,
Qi Wu,
Yuanyuan Liu,
Guowei Huang,
Hua Yan,
Clement C Tham,
Jing Yan,
Qiang Yang,
Ruihua Wei,
Xiangda Meng,
Tongtong Li,
Bei Du,
Chea-Su Kee,
Xuyang Yao,
Yuezhu Lu,
Qihua Wang
Affiliations
Jing Yang
Department of Oncology, Chinese PLA General Hospital Second Medical Center, Beijing, China
Qi Wu
School of Public Health, Tianjin Medical University, Tianjin, China
Yuanyuan Liu
Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, China
Guowei Huang
School of Public Health, Tianjin Medical University, Tianjin, China
Hua Yan
Department of Ophthalmology, Tianjin Medical University General Hospital, Laboratory of Molecular Ophthalmology, Tianjin Medical University, Tianjin, China
Clement C Tham
Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong KonSARg, China
Jing Yan
School of Public Health, Tianjin Medical University, Tianjin, China
Qiang Yang
Shenyang Xingqi Pharmaceutical Co., Ltd, Shenyang, China
Ruihua Wei
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China
Xiangda Meng
Tianjin Key Laboratory of Ocular Trauma, Tianjin, China
Tongtong Li
School of Public Health, Tianjin Medical University, Tianjin, China
Bei Du
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China
Chea-Su Kee
School of Optometry, Centre for Myopia Research, Research Centre for SHARP Vision, The Hong Kong Polytechnic University, Hong Kong, China
Xuyang Yao
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China
Yuezhu Lu
Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
Qihua Wang
Department of Ophthalmology, Tianjin Medical University General Hospital, Laboratory of Molecular Ophthalmology, Tianjin Medical University, Tianjin, China
Objectives This study aimed to explore the influence of the interaction between parental myopia and lifestyle on myopia among school-age children.Design Cross-sectional study.Setting This study used data from the Tianjin Child and Adolescent Research of Eye between August and October 2022.Participants A total of 49 035 participants between 6 and 18 years of age were eligible for this study.Primary and secondary outcome measures The primary outcome was the interaction between eye-healthy lifestyle and parental myopia on myopia. Parental myopia and eye-healthy lifestyle were ascertained by a Child and Adolescent Behavior Questionnaire. The lifestyle risk score (LRS) of eye health was calculated based on beta-coefficient in the backward regression model. The interaction between LRS and parental myopia was analysed by multivariate logistic regression. The predictive value of different predicted models was estimated using receiver operating characteristic curves. Multiple linear regression was used to evaluate the associations of lifestyle risk factors and parental myopia with spherical equivalent refraction, which were defined as the secondary outcomes.Results A total of 31 839 participants aged 6–18 years were included, and the myopia prevalence was 55.46%. Eye-healthy lifestyle and parental myopia were significantly associated with myopia, as was interaction. The predictive value for LRS & parental myopia was 0.714 (95% CI: 0.709 to 0.720), which was higher than LRS (0.693, 95% CI: 0.687 to 0.699) and parental myopia (0.710, 95% CI: 0.704 to 0.716) separately.Conclusions High-risk lifestyles of myopia and parental myopia were significantly associated with a higher risk of myopia, and the combination had the strongest effect. For children, lifestyle adjustment should be prioritised in preventing myopia, especially for those with parental myopia.