Extracellular vesicles, tissue factor, cancer and thrombosis – discussion themes of the ISEV 2014 Educational Day

Chris Gardiner; Paul Harrison; Mattias Belting; Anita Böing; Elena Campello; Bob S. Carter; Mary E. Collier; Frank Coumans; Camille Ettelaie; Nick van Es; Fred H. Hochberg; Nigel Mackman; Robert C. Rennert; Johannes Thaler; Janusz Rak; Rienk Nieuwland

doi:10.3402/jev.v4.26901

Journal of Extracellular Vesicles (Mar 2015)

Extracellular vesicles, tissue factor, cancer and thrombosis – discussion themes of the ISEV 2014 Educational Day

Chris Gardiner,
Paul Harrison,
Mattias Belting,
Anita Böing,
Elena Campello,
Bob S. Carter,
Mary E. Collier,
Frank Coumans,
Camille Ettelaie,
Nick van Es,
Fred H. Hochberg,
Nigel Mackman,
Robert C. Rennert,
Johannes Thaler,
Janusz Rak,
Rienk Nieuwland

Affiliations

Chris Gardiner: Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Level 3 Women's Centre, John Radcliffe Hospital, Oxford, UK
Paul Harrison: School of Immunity and Infection, University of Birmingham Medical School, Birmingham, UK
Mattias Belting: Department of Oncology and Pathology, Clinical Sciences, Skåne University Hospital, Lund, Sweden
Anita Böing: Department of Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands
Elena Campello: Department of Cardiologic, Thoracic and Vascular Sciences, University of Padua Medical School, Padua, Italy
Bob S. Carter: Division of Neurosurgery, University of California San Diego, La Jolla, CA, USA
Mary E. Collier: Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Wing, Glenfield General Hospital, Leicester, UK
Frank Coumans: Department of Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands
Camille Ettelaie: School of Biological, Biomedical and Environmental Sciences, The University of Hull, Hull, UK
Nick van Es: Department of Vascular Medicine, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands
Fred H. Hochberg: Division of Neurosurgery, University of California San Diego, La Jolla, CA, USA
Nigel Mackman: Thrombosis and Hemostasis Program, Department of Medicine, UNC McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Robert C. Rennert: Division of Neurosurgery, University of California San Diego, La Jolla, CA, USA
Johannes Thaler: Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
Janusz Rak: Department of Pediatrics, McGill University, Montreal Children's Hospital Research Institute MUHC, Montreal, QC, Canada
Rienk Nieuwland: Department of Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands

DOI: https://doi.org/10.3402/jev.v4.26901
Journal volume & issue: Vol. 4, no. 0
pp. 1 – 14

Abstract

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Although the association between cancer and venous thromboembolism (VTE) has long been known, the mechanisms are poorly understood. Circulating tissue factor–bearing extracellular vesicles have been proposed as a possible explanation for the increased risk of VTE observed in some types of cancer. The International Society for Extracellular Vesicles (ISEV) and International Society on Thrombosis and Haemostasis (ISTH) held a joint Educational Day in April 2014 to discuss the latest developments in this field. This review discusses the themes of that event and the ISEV 2014 meeting that followed.

Published in Journal of Extracellular Vesicles

ISSN: 2001-3078 (Online)
Publisher: Wiley
Country of publisher: United States
LCC subjects: Science: Biology (General): Cytology
Website: https://isevjournals.onlinelibrary.wiley.com/journal/20013078

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