Condensation reaction of benzil with resorcinol and the establish-ment of the spectral data as well as cytotoxicity study

Abstract

Condensation of benzil, 1 with resorcinol in the presence of potassium carbonate at 110-120˚C gave the mixture of the compounds. Using various kinds of separation technique only five types of the polymeric products, a1, a2, a3, a4 and a5 were isolated. The compounds a1, a4 showed high cytotoxic activity and the compounds a2, a3 and a5 showed relatively low cytotoxic activity against the brine shrimp lethality bioassay.

Keywords

• benzil
• resorcinol
• cytotoxic