Effect of Echinacea Purpurea Extract and Thiotriazoline on the Muscular Membrane of the Pyloric Part of the Stomach of Rats under the Action of Epichlorohydrin

Abstract

During the experiments on white rats, the changes occurring in the muscular membrane of pyloric part of rats’ stomach after a two-month inhalation exposure to epichlorohydrin, Echinacea purpurea extract and thiotriazoline administration were studied. It has been shown that one of the manifestations of epichlorohydrin action was decrease in the thickness of the muscular membrane in pyloric part of rats’ stomach. The degree of reduction of the muscular membrane thickness during the period between the first on the sixtieth day after inhalation decreased. Introduction of Echinacea purpurea extract as well as thiotriazoline was accompanied by thickening of the muscular membrane of pyloric part of the stomach. Echinacea purpurea extract and thiotriazoline showed the ability to reduce the period of reduction of the muscle membrane thickness induced by epichlorohydrin from sixty to seven days.

Keywords

• stomach
• epichlorohydrin
• echinacea purpurea extract
• thiotriazoline
• rats